Antivirulence activity of auranofin against vancomycin-resistant enterococci: in vitro and in vivo studies
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منابع مشابه
Efficacy of hand disinfectants against vancomycin-resistant enterococci in vitro.
Vancomycin-resistant enterococci (VRE) may be spread within a hospital via the contaminated hands of the healthcare worker. Effective hand disinfectants are necessary to break chains of transmission. We determined the bactericidal activity of 1-propanol, chlorhexidine digluconate (0.5 and 4%). Sterillium (45% 2-propanol, 30% 1-propanol and 0.2% mecetronium etilsulphate), Skinsept F (70% 2-propa...
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The activity of nitrofurantoin was tested against 300 isolates of Enterococcus faecium, Enterococcus faecalis, and Enterococcus gallinarum. No isolates tested were resistant to nitrofurantoin (MIC, >/=128 microg/ml), including vancomycin-resistant E. faecium isolates with vanA- and vanB-positive genotypes and vancomycin-resistant E. gallinarum isolates. We conclude that nitrofurantoin may provi...
متن کاملAbsence of synergistic activity between ampicillin and vancomycin against highly vancomycin-resistant enterococci.
The emergence of clinical enterococcal isolates resistant to both ampicillin and vancomycin is a cause of great concern, as there are few therapeutic alternatives for treatment of infections caused by such organisms. We evaluated the effects of the combination of ampicillin with vancomycin against vancomycin-resistant clinical enterococcal isolates. Using both the checkerboard technique and tim...
متن کاملIn vitro susceptibilities of clinical isolates of vancomycin-resistant enterococci.
Recent studies have reported RP59500 (Synercid) (quinupristin-dalfopristin), a semisynthetic streptogramin, to have good in vitro activity against certain enterococcal strains, including vancomycin-resistant strains of Enterococcus faecium (3–5). The purpose of the present study was to determine the in vitro activity of this new compound against a larger sample of resistant strains of enterococ...
متن کاملIn-vitro and In-vivo Evaluation of Silymarin Nanoliposomes against Isolated Methicillin-resistant Staphylococcus aureus
Staphylococcus aureus is an opportunistic pathogen and remains a common cause of burn wound infections. Different studies have shown that entrapment of plant-derived compounds into liposomes could increase their anti-Staphylococcus aureus activity. Silymarin is the bioactive extract from the known plant Silybum marianum L. The objective of this study was to evaluate efficacy of silymarin in fre...
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ژورنال
عنوان ژورنال: International Journal of Antimicrobial Agents
سال: 2020
ISSN: 0924-8579
DOI: 10.1016/j.ijantimicag.2019.10.009